INT349527

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.93
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Smcp) cytoplasm (Smcp)
Smcp (Mus musculus)
Pain Link Frequency Relevance Heat
fortral 16 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Melanoma 252 98.76 Very High Very High Very High
Malignant Neoplastic Disease 16 98.60 Very High Very High Very High
Apoptosis 192 98.20 Very High Very High Very High
Cancer 132 77.68 Quite High
Toxicity 20 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Carcinoma 8 5.00 Very Low Very Low Very Low
Dislocations 4 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, anti-MCSP:TRAIL dephosphorylates a panel of established MCSP targets as well as newly identified proteins (see Additional file 2, Table S1 for overview).
Phosphorylation (dephosphorylates) of anti-MCSP
1) Confidence 0.58 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.71 Pain Relevance 0
Taken together, anti-MCSP:TRAIL dephosphorylates a panel of established MCSP targets as well as newly identified proteins (see Additional file 2, Table S1 for overview).
Phosphorylation (dephosphorylates) of MCSP
2) Confidence 0.50 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.71 Pain Relevance 0
Anti-MCSP:TRAIL dephosphorylates proteins involved in cell proliferation and apoptosis resistance
Phosphorylation (dephosphorylates) of Anti-MCSP associated with apoptosis
3) Confidence 0.45 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.39 Pain Relevance 0
First and foremost, the previously reported down-stream target of MCSP, FAK, was dephosphorylated by a factor 2 compared to medium control.
Phosphorylation (dephosphorylated) of MCSP
4) Confidence 0.45 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.12 Pain Relevance 0

General Comments

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