INT349542

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnfsf10)
SCFV (Homo sapiens)
Tnfsf10 (Mus musculus)
Pain Link Frequency Relevance Heat
fortral 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 48 94.52 High High
Melanoma 63 71.20 Quite High
Malignant Neoplastic Disease 4 35.68 Quite Low
Cancer 33 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Carcinoma 2 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previously, we and others have shown that upon binding to the respective target antigen, scFv:TRAIL fusion proteins can efficiently activate TRAIL-R2, whereas untargeted sTRAIL preparations have a markedly reduced capacity to activate TRAIL-R2 signaling.
scFv Positive_regulation (activate) of TRAIL
1) Confidence 0.12 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.56 Pain Relevance 0

General Comments

This test has worked.

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