INT349586

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) plasma membrane (Ros1)
Aap (Mus musculus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 166 100.00 Very High Very High Very High
Dopamine 1 61.68 Quite High
cINOD 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 19 100.00 Very High Very High Very High
Overdose 9 99.34 Very High Very High Very High
Liver Failure 1 98.86 Very High Very High Very High
Stress 2 75.52 Quite High
Drug Induced Neurotoxicity 6 56.04 Quite High
Apoptosis 16 50.00 Quite Low
Alzheimer's Dementia 1 49.20 Quite Low
Hepatotoxicity 5 34.16 Quite Low
Death 46 23.56 Low Low
Acute Liver Failure 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, several recent studies have shown the protective effects of antioxidants on hepatic failure induced by AAP overdose [32]–[34], indicating that high AAP concentrations, far from protecting cells from ROS toxicity, actually contribute to ROS production.
AAP Regulation (contribute) of Gene_expression (production) of ROS associated with liver failure, toxicity, paracetamol and overdose
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000821 Disease Relevance 0.56 Pain Relevance 1.17

General Comments

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