INT349588

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.73
Pain Relevance 1.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) plasma membrane (Ros1)
Aap (Mus musculus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 332 100.00 Very High Very High Very High
Dopamine 2 55.56 Quite High
cINOD 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 38 96.40 Very High Very High Very High
Overdose 18 92.56 High High
Liver Failure 2 91.60 High High
Death 92 87.92 High High
Stress 4 69.40 Quite High
Hepatotoxicity 10 56.80 Quite High
Apoptosis 32 50.00 Quite Low
Drug Induced Neurotoxicity 12 49.92 Quite Low
Alzheimer's Dementia 2 43.08 Quite Low
Acute Liver Failure 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In agreement with these data, we have shown that AAP increases ROS production in a concentration-dependent manner 18 h after treatment.
AAP Positive_regulation (increases) of Gene_expression (production) of ROS associated with paracetamol
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000821 Disease Relevance 0.42 Pain Relevance 1.03
The results showed that AAP increased the rate of ROS production in a concentration-dependent manner (Figure 5B).
AAP Positive_regulation (increased) of Gene_expression (production) of ROS associated with paracetamol
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000821 Disease Relevance 0.31 Pain Relevance 0.82

General Comments

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