INT349609

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LMOD1) cytoskeleton (LMOD1) cytoplasm (LMOD1)
LMOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 92 99.84 Very High Very High Very High
antagonist 34 98.82 Very High Very High Very High
Substantia nigra 4 93.84 High High
agonist 32 91.44 High High
dopamine receptor 9 50.00 Quite Low
Pain 1 14.72 Low Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
deep brain stimulation 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dyskinesias 16 96.04 Very High Very High Very High
Muscle Hypotonia 2 79.76 Quite High
Hyperkinesis 2 44.16 Quite Low
Dystonia 9 40.08 Quite Low
Hypokinesia 12 34.32 Quite Low
Muscle Rigidity 4 30.36 Quite Low
Parkinson's Disease 14 11.40 Low Low
Multiple System Atrophy 1 8.52 Low Low
Supranuclear Palsy 1 7.68 Low Low
Tremor 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to our model, D1 antagonists inhibit dopamine/D1 interactions, so that dopamine cannot realize its action on D1 receptors and cannot cause tone reduction.
Regulation (realize) of Regulation (action) of D1 associated with dopamine and antagonist
1) Confidence 0.41 Published 2010 Journal J Neural Transm Section Body Doc Link PMC3000910 Disease Relevance 0.65 Pain Relevance 0.63

General Comments

This test has worked.

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