INT349651

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.46
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Rela) DNA binding (Rela) protein complex (Rela)
response to stress (Rela) cytoplasm (Rela) cytosol (Rela)
Anatomy Link Frequency
macrophage 2
Rela (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 44 96.52 Very High Very High Very High
Inflammation 27 92.16 High High
cytokine 10 88.64 High High
chemokine 2 85.84 High High
Inflammatory response 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ureteral Obstruction 45 99.78 Very High Very High Very High
Apoptosis 5 97.60 Very High Very High Very High
Fibrosis 54 96.52 Very High Very High Very High
INFLAMMATION 31 92.16 High High
Cv Unclassified Under Development 2 89.96 High High
Adhesions 2 82.72 Quite High
Chronic Renal Failure 6 76.56 Quite High
Renal Disease 10 71.04 Quite High
Internal Fibrosis 9 46.16 Quite Low
Stress 4 45.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In UUO, there is activation of the renin┬ľangiotensin system with production of reactive oxygen species (ROS) and NFkB, which promote macrophage infiltration [37], renal tubular apoptosis and interstitial fibrosis [38].
Positive_regulation (activation) of Gene_expression (production) of NFkB in macrophage associated with fibrosis, ureteral obstruction and apoptosis
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001459 Disease Relevance 1.46 Pain Relevance 0.33

General Comments

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