INT349652

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hmox1, Itk) endoplasmic reticulum (Hmox1) enzyme binding (Hmox1)
cytoplasm (Itk) signal transducer activity (Hmox1) signal transduction (Hmox1)
Hmox1 (Rattus norvegicus)
Itk (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 1 93.68 High High
Inflammation 27 78.80 Quite High
fibrosis 44 77.60 Quite High
cytokine 10 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Disease 10 86.80 High High
Fibrosis 54 84.72 Quite High
INFLAMMATION 31 78.80 Quite High
Chronic Renal Failure 6 67.08 Quite High
Cicatrix 7 30.12 Quite Low
Ureteral Obstruction 45 29.28 Quite Low
Internal Fibrosis 9 25.80 Quite Low
Proteinuria 7 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Albuminuria 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An in vitro study demonstrated that HO-1 upregulation could prevent cyclosporine A-induced EMT via NRF2, a master regulator of genes associated with the cellular antioxidant system [54].
Positive_regulation (upregulation) of HO-1 Negative_regulation (prevent) of Positive_regulation (induced) of EMT
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001459 Disease Relevance 0.85 Pain Relevance 0.25

General Comments

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