INT349758

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Galr1) extracellular region (Gal) Golgi apparatus (Gal)
plasma membrane (Galr1) signal transducer activity (Galr1) cytoplasm (Gal)
Anatomy Link Frequency
hippocampus 1
Gal (Mus musculus)
Galr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuronal excitability 5 98.00 Very High Very High Very High
Hippocampus 22 96.84 Very High Very High Very High
Neuropeptide 2 90.68 High High
antagonist 15 48.72 Quite Low
Pyramidal cell 7 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 64 84.72 Quite High
Death 40 82.08 Quite High
Targeted Disruption 12 77.12 Quite High
Status Epilepticus 7 68.80 Quite High
Sprains And Strains 12 40.32 Quite Low
Injury 9 35.20 Quite Low
Epilepsy 14 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several lines of evidence indicate that galanin, as well as activation of the GalR1 receptor, is a potent and effective modulator of neuronal excitability in the hippocampus.


galanin Positive_regulation (activation) of GalR1 in hippocampus associated with neuronal excitability and hippocampus
1) Confidence 0.37 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3001489 Disease Relevance 0.44 Pain Relevance 0.14

General Comments

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