INT349818

Context Info Confidence 0.20 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.22 Pain Relevance 0.09

extracellular space (Tgfa) extracellular region (Tgfa) plasma membrane (Tgfa) nucleus (Tgfa)

Anatomy Link Frequency neuronal 1 Tgfa (Mus musculus)

Pain Link Frequency Relevance Heat Neuropeptide 5 86.56 Spinal cord 17 40.16 Inflammation 8 5.00 dorsal root ganglion 6 5.00 Inflammatory response 6 5.00 Central nervous system 2 5.00 cerebral cortex 1 5.00 Peripheral nerve injury 1 5.00 ketamine 1 5.00 Nerve growth factor 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 24 73.28 Nervous System Malformation 1 70.24 Injury 35 7.76 Spinal Cord Injury 29 5.00 INFLAMMATION 14 5.00 Death 12 5.00 Spinal Injuries 8 5.00 Ganglion Cysts 7 5.00 Contusions 6 5.00 Stress 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Eight of these genes encode neurotrophic/growth factor receptors (Lifr, Crhr1, Gfra2, Gfra1, Ntrk2, Ntrk1, Cntfr, and Adcyap1r1), and 7 encode agents that enhance neuronal survival or axonal regeneration (Hspb1, Ntf5, Tgfa, Zfp91, Artn, Tgfb1, and Mt3).

Positive_regulation (enhance) of Tgfa in neuronal

1) Confidence 0.20 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0.22 Pain Relevance 0.09

General Comments

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