INT349849

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Adcyap1r1) endosome (Adcyap1r1) plasma membrane (Adcyap1r1)
cytoplasm (Adcyap1r1) signal transducer activity (Adcyap1r1)
Gfra2 (Rattus norvegicus)
Adcyap1r1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 1 90.72 High High
Inflammatory response 6 85.00 Quite High
Nerve growth factor 1 66.08 Quite High
Spinal cord 17 57.48 Quite High
Inflammation 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 6 5.00 Very Low Very Low Very Low
Neuropeptide 5 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Peripheral nerve injury 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Cord Injury 29 87.76 High High
INFLAMMATION 14 84.64 Quite High
Frailty 2 76.24 Quite High
Injury 35 46.52 Quite Low
Death 12 43.88 Quite Low
Apoptosis 24 32.16 Quite Low
Spinal Injuries 8 5.00 Very Low Very Low Very Low
Ganglion Cysts 7 5.00 Very Low Very Low Very Low
Contusions 6 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found the simultaneous down-regulation of three out of the four receptors of the GDNF family (Gfra1, Gfra2, Gfra3), as well as the down regulation of Ntrk1 (TrkA) and the Adcyap1r1 receptor.
Gfra2 Negative_regulation (regulation) of Adcyap1r1
1) Confidence 0.33 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0.31 Pain Relevance 0.15

General Comments

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