INT349908

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.13
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ctnnd1) cell adhesion (Ctnnd1) plasma membrane (Ctnnd1)
nucleus (Ctnnd1) cytoplasm (Ctnnd1)
Anatomy Link Frequency
p120 2
Ctnnd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 18 77.20 Quite High
addiction 2 46.28 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 24 96.92 Very High Very High Very High
Familial Adenomatous Polyposis 2 93.64 High High
Cancer 6 91.04 High High
Disease 24 77.20 Quite High
Inflammatory Bowel Disease 4 64.84 Quite High
Pathologic Processes 2 59.12 Quite High
Adhesions 6 48.76 Quite Low
Peritonitis 2 17.04 Low Low
Bacterial Respiratory Disease 6 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indirect data generated by over-expression of a dominant-negative N-cadherin or targeting p120-catenin suggest an important role in intestinal homeostasis [14], [15].
Gene_expression (expression) of p120-catenin in p120
1) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001873 Disease Relevance 0.82 Pain Relevance 0.10
Targeted deletion of the E-cadherin interacting protein p120-catenin led to a disrupted intestinal barrier and impaired epithelial homeostasis [15].
Gene_expression (deletion) of p120-catenin in p120
2) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001873 Disease Relevance 0.31 Pain Relevance 0

General Comments

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