INT349912

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.04
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdh1) cell adhesion (Cdh1) Golgi apparatus (Cdh1)
plasma membrane (Cdh1) cytoplasm (Cdh1)
Cdh1 (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 27 96.56 Very High Very High Very High
addiction 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 6 99.90 Very High Very High Very High
Infection 9 98.40 Very High Very High Very High
Disease 36 96.24 Very High Very High Very High
Apoptosis 36 94.32 High High
Diarrhoea 6 67.12 Quite High
Body Weight 9 65.00 Quite High
Bacterial Respiratory Disease 9 63.88 Quite High
Adhesions 9 50.40 Quite High
Targeted Disruption 3 36.96 Quite Low
Cancer 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Induction of cell death and loss of adherens junctions and differentiated cells upon loss of E-cadherin
Negative_regulation (loss) of Negative_regulation (loss) of E-cadherin associated with death
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001873 Disease Relevance 0.59 Pain Relevance 0
Down-regulation of E-cadherin is associated with the pathogenesis of infections with enteropathogenic bacteria and Crohn's disease.


Negative_regulation (Down) of Negative_regulation (regulation) of E-cadherin associated with crohn's disease, disease and infection
2) Confidence 0.42 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3001873 Disease Relevance 0.39 Pain Relevance 0.05
Impairment of bacterial defense after loss of E-cadherin
Negative_regulation (Impairment) of Negative_regulation (loss) of E-cadherin
3) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001873 Disease Relevance 0.06 Pain Relevance 0

General Comments

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