INT349951

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grm7) Golgi apparatus (Grm7) plasma membrane (Grm7)
neurological system process (Grm7) protein complex (Grm7) signal transducer activity (Grm7)
Grm7 (Mus musculus)
pcp (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 49 100.00 Very High Very High Very High
nMDA receptor antagonist 7 59.00 Quite High
Glutamate 34 50.00 Quite Low
nMDA receptor 19 36.80 Quite Low
Eae 12 23.76 Low Low
antagonist 68 5.00 Very Low Very Low Very Low
antidepressant 20 5.00 Very Low Very Low Very Low
depression 19 5.00 Very Low Very Low Very Low
ketamine 10 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 12 98.60 Very High Very High Very High
Schizophrenia 33 92.00 High High
Cognitive Disorder 20 50.64 Quite High
Congenital Anomalies 5 22.56 Low Low
Targeted Disruption 6 18.64 Low Low
Psychosis 1 7.08 Low Low
Depression 20 5.00 Very Low Very Low Very Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the effects of mGlu2/3 receptor agonists on PCP- or amphetamine-induced locomotor hyperactivity were mimicked by the selective mGlu2 receptor potentiator N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethylsulfonyl)pyrid-3-ylmethylamine (LY487379) [24].
mGlu2/3 receptor Regulation (effects) of PCP associated with agonist and attention deficit hyperactivity disorder
1) Confidence 0.00 Published 2010 Journal The Open Medicinal Chemistry Journal Section Body Doc Link PMC3002053 Disease Relevance 0.56 Pain Relevance 0.28

General Comments

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