INT350069

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Prkaca, Hmox1) mitochondrion (Prkaca) endoplasmic reticulum (Hmox1)
Golgi apparatus (Prkaca) enzyme binding (Hmox1) protein complex (Prkaca)
Prkaca (Mus musculus)
Hmox1 (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 2 95.68 Very High Very High Very High
Inflammation 21 63.96 Quite High
cytokine 3 46.80 Quite Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 7 83.76 Quite High
INFLAMMATION 19 63.96 Quite High
Bacterial Infection 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Vasculitis 4 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Sepsis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Adenovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, it has been also reported that the COX-2 metabolite, PGE2, induces HO-1 through PKA and PI3K signaling pathways via EP2 receptors in C6 cells [50].
PKA Positive_regulation (induces) of HO-1
1) Confidence 0.05 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3002338 Disease Relevance 0.20 Pain Relevance 0.15

General Comments

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