INT350071

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Hmox1, Tlr4) endoplasmic reticulum (Hmox1) intracellular (Tlr4)
enzyme binding (Hmox1) cytoplasm (Tlr4) signal transducer activity (Hmox1)
Anatomy Link Frequency
endothelial cell 1
Hmox1 (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 21 67.92 Quite High
cytokine 3 19.24 Low Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 6 71.04 Quite High
Vasculitis 4 68.64 Quite High
Bacterial Infection 6 65.12 Quite High
Stress 7 61.36 Quite High
Brain Injury 1 46.12 Quite Low
INFLAMMATION 19 45.44 Quite Low
Encephalitis 1 39.28 Quite Low
Sepsis 2 14.36 Low Low
Syndrome 1 11.28 Low Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, experiments were performed using a mouse brain endothelial cell line (bEnd.3) to investigate whether HO-1 regulates LPS-induced COX-2 expression in these cells.
HO-1 Spec (whether) Regulation (regulates) of LPS in endothelial cell
1) Confidence 0.22 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3002338 Disease Relevance 0.33 Pain Relevance 0.03

General Comments

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