INT350099

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Hmox1) enzyme binding (Hmox1) signal transducer activity (Hmox1)
cytosol (Hmox1) signal transduction (Hmox1) cell death (Hmox1)
Hmox1 (Mus musculus)
MRXS5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 21 84.00 Quite High
Pain 1 67.36 Quite High
Inflammatory response 2 65.00 Quite High
cytokine 3 44.40 Quite Low
Inflammatory mediators 1 36.88 Quite Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 19 84.00 Quite High
Pain 1 67.36 Quite High
Vasculitis 4 59.68 Quite High
Bacterial Infection 6 56.88 Quite High
Injury 6 51.12 Quite High
Stress 7 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Sepsis 2 5.00 Very Low Very Low Very Low
Adenovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that overexpression of HO-1 exerts an inhibitory effect on COX-2 expression and PGs production in different cell types.
Gene_expression (overexpression) of HO-1 Positive_regulation (exerts) of Gene_expression (production) of PGs
1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3002338 Disease Relevance 0.51 Pain Relevance 0.24

General Comments

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