INT35011

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Context Info
Confidence 0.48
First Reported 1987
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.52
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (PPFIBP1) plasma membrane (PPFIBP1)
Anatomy Link Frequency
epithelial cells 1
bladder 1
PPFIBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dysuria 1 83.84 Quite High
imagery 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurofibroma 4 99.42 Very High Very High Very High
Papillomavirus Infection 685 98.28 Very High Very High Very High
Acoustic Neuroma 1 94.00 High High
Diuresis 1 92.92 High High
Neurilemmoma 1 92.16 High High
Infection 140 89.76 High High
Overactive Bladder 3 89.04 High High
Injury 2 87.44 High High
Incontinence 1 84.60 Quite High
Carcinoma 3 76.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In case B, cystometrogram was initially normal, but changed to inactive bladder type one year later and neurofibromas were found in the vertebral bodies of Th7-8 and L2.
Gene_expression (bodies) of L2 in bladder associated with neurofibroma
1) Confidence 0.48 Published 1987 Journal Hinyokika Kiyo Section Abstract Doc Link 3107355 Disease Relevance 1.12 Pain Relevance 0.08
HPV early genes are expressed throughout this life cycle, while late capsid genes L1 and L2 are only expressed in terminally differentiated epithelial cells.
Gene_expression (expressed) of L2 in epithelial cells associated with papillomavirus infection
2) Confidence 0.07 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 1.54 Pain Relevance 0
Following entry into the suprabasal layers, expression of the late viral genes E4, L1, and L2 is initiated; the circular viral genome is then replicated and structural proteins form.
Gene_expression (expression) of L2
3) Confidence 0.02 Published 2008 Journal Infect Agent Cancer Section Body Doc Link PMC2628336 Disease Relevance 1.87 Pain Relevance 0

General Comments

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