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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.48
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (INS, SHBG) extracellular space (INS) small molecule metabolic process (INS)
carbohydrate metabolic process (INS) cell-cell signaling (INS)
Anatomy Link Frequency
blood 2
INS (Homo sapiens)
SHBG (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 2 86.56 High High
antagonist 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hirsutism 26 96.72 Very High Very High Very High
Hyperinsulinism 4 92.40 High High
Insulin Resistance 6 91.60 High High
Syndrome 6 90.04 High High
Polycystic Ovary Syndrome 52 87.64 High High
Addisons Disease 1 74.84 Quite High
Reprotox - General 1 5 74.00 Quite High
Alagille Syndrome 3 71.04 Quite High
Congenital Adrenal Hyperplasia 3 67.36 Quite High
Adrenal Cancer 2 61.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, insulin is able to lower SHBG serum levels leading to an increase in free testosterone in the peripheral blood.[15]


insulin Negative_regulation (lower) of Positive_regulation (leading) of SHBG in blood associated with hirsutism
1) Confidence 0.09 Published 2010 Journal International Journal of Trichology Section Body Doc Link PMC3002408 Disease Relevance 1.48 Pain Relevance 0.04

General Comments

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