INT350148

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 8.23
Pain Relevance 2.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) intracellular (ERAL1) ribosome biogenesis (ERAL1)
cytoplasm (IL12A) extracellular space (IL12A) extracellular region (IL12A)
IL12A (Homo sapiens)
ERAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 215 100.00 Very High Very High Very High
rheumatoid arthritis 30 89.84 High High
spinal inflammation 10 66.44 Quite High
cytokine 5 17.96 Low Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 40 100.00 Very High Very High Very High
Juvenile Chronic Polyarthritis 175 98.28 Very High Very High Very High
Lipoma 30 94.60 High High
Disease 110 92.68 High High
Diabetes Mellitus 75 90.04 High High
Rheumatoid Arthritis 30 89.84 High High
Autoimmune Disease 45 89.48 High High
Disease Susceptibility 15 87.28 High High
Celiac Disease 15 75.00 Quite High
Low Back Pain 10 66.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, we report an ERA subtype-specific association with the IL12A gene.
IL12A Binding (association) of ERA associated with arthritis
1) Confidence 0.21 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 1.73 Pain Relevance 0.51
In addition, a subtype-specific association of IL12A with ERA is identified.
IL12A Binding (association) of ERA associated with arthritis
2) Confidence 0.18 Published 2010 Journal Annals of the Rheumatic Diseases Section Abstract Doc Link PMC3002762 Disease Relevance 1.64 Pain Relevance 0.47
The SNP, rs17810546, in IL12A showed subtype-specific association with enthesitis-related arthritis (ERA) subtype (ptrend=0.005, OR=1.88, 95% CI 1.2 to 2.94).


IL12A Binding (association) of ERA associated with arthritis
3) Confidence 0.16 Published 2010 Journal Annals of the Rheumatic Diseases Section Abstract Doc Link PMC3002762 Disease Relevance 1.83 Pain Relevance 0.50
The enthesitis-related arthritis (ERA) subtype showed strong association with IL12A SNP (ptrend=0.005, OR=1.88, 95% CI 1.2 to 2.94).
IL12A Binding (association) of ERA associated with arthritis
4) Confidence 0.16 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 1.29 Pain Relevance 0.28
In addition, we report an ERA subtype-specific association with the IL12A gene.
IL12A Binding (association) of ERA associated with arthritis
5) Confidence 0.16 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 1.73 Pain Relevance 0.51

General Comments

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