INT350149

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SH2B3) cytosol (SH2B3) extracellular region (CD8A)
plasma membrane (CD8A) signal transducer activity (SH2B3)
Anatomy Link Frequency
T-cell 1
SH2B3 (Homo sapiens)
CD8A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 99.12 Very High Very High Very High
rheumatoid arthritis 6 93.44 High High
Arthritis 43 79.04 Quite High
spinal inflammation 2 22.88 Low Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 93.72 High High
Rheumatoid Arthritis 6 93.44 High High
Cancer 1 91.28 High High
Necrosis 1 90.72 High High
Juvenile Chronic Polyarthritis 35 79.04 Quite High
Autoimmune Disease 9 74.84 Quite High
Lipoma 6 59.20 Quite High
Adhesions 1 56.28 Quite High
Diabetes Mellitus 15 50.00 Quite Low
Disease Susceptibility 3 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SH2B3 encodes the T-cell adapter protein Lnk, which regulates T-cell receptor-, growth factor- and cytokine receptor-mediated signalling.
Lnk Regulation (regulates) of T-cell receptor in T-cell associated with cytokine
1) Confidence 0.13 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 0.86 Pain Relevance 0.17

General Comments

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