INT350151

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SH2B3) cytosol (SH2B3) nucleoplasm (SNRNP70)
mRNA processing (SNRNP70) RNA binding (SNRNP70) nucleus (SNRNP70)
SNRNP70 (Homo sapiens)
SH2B3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 43 99.04 Very High Very High Very High
rheumatoid arthritis 6 69.20 Quite High
cytokine 1 51.28 Quite High
spinal inflammation 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 35 99.04 Very High Very High Very High
Autoimmune Disease 9 98.64 Very High Very High Very High
Lipoma 6 83.00 Quite High
Adhesions 1 80.08 Quite High
Disease 22 73.92 Quite High
Rheumatoid Arthritis 6 69.20 Quite High
Diabetes Mellitus 15 52.68 Quite High
Disease Susceptibility 3 50.00 Quite Low
Celiac Disease 3 50.00 Quite Low
Cancer 1 44.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also found weak evidence for association of a SNP, rs653178, in the SH2B3/ATXN2 gene region with JIA, though it did not remain significant after correction for multiple testing.
SNP Binding (association) of SH2B3 associated with arthritis
1) Confidence 0.13 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 1.22 Pain Relevance 0.20

General Comments

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