INT350157

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 3.53
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (ATXN2) Golgi apparatus (ATXN2) nucleolus (ATXN2)
RNA binding (ATXN2) nucleus (ATXN2) cytoplasm (ATXN2)
ATXN2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 86 98.88 Very High Very High Very High
rheumatoid arthritis 12 93.76 High High
spinal inflammation 4 70.36 Quite High
cytokine 2 21.88 Low Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lipoma 12 99.26 Very High Very High Very High
Juvenile Chronic Polyarthritis 70 98.88 Very High Very High Very High
Arthritis 16 94.64 High High
Disease 44 94.24 High High
Diabetes Mellitus 30 93.96 High High
Rheumatoid Arthritis 12 93.76 High High
Autoimmune Disease 18 93.40 High High
Disease Susceptibility 6 75.00 Quite High
Celiac Disease 6 75.00 Quite High
Low Back Pain 4 70.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion we have identified novel association of the LPP gene and show weak but confirmatory association of the ATXN2/SH2B3/c12orf30 region with JIA in a UK cohort.
ATXN2 Binding (association) of associated with lipoma and arthritis
1) Confidence 0.33 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 1.80 Pain Relevance 0.54
Association at the SH2B3/ATXN2 locus, previously reported to be associated with JIA in a US series, also supports this region as contributing to JIA susceptibility.
ATXN2 Binding (Association) of associated with arthritis
2) Confidence 0.33 Published 2010 Journal Annals of the Rheumatic Diseases Section Abstract Doc Link PMC3002762 Disease Relevance 1.73 Pain Relevance 0.49

General Comments

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