INT3503

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Context Info
Confidence 0.65
First Reported 1976
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.17
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL11A1) cell adhesion (COL11A1) protein binding, bridging (COL11A1)
extracellular matrix organization (COL11A1)
Anatomy Link Frequency
stellate cells 1
COL11A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 1 98.56 Very High Very High Very High
adenocard 1 97.28 Very High Very High Very High
local anesthetic 4 95.36 Very High Very High Very High
Osteoarthritis 84 88.28 High High
Arthritis 16 71.96 Quite High
chemokine 1 58.80 Quite High
Inflammation 23 50.00 Quite Low
Chronic pancreatitis 9 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 46 97.80 Very High Very High Very High
Primary Sclerosing Cholangitis 31 96.32 Very High Very High Very High
Disease 36 94.04 High High
Frailty 85 88.28 High High
Injury 6 79.08 Quite High
Experimental Arthritis 2 71.96 Quite High
Arthritis 19 68.08 Quite High
Adhesions 3 65.28 Quite High
Cancer 47 50.00 Quite Low
INFLAMMATION 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-localization of alpha-smooth muscle actin (red) and Col11a1 (green) in stellate cells in pancreatic tissues is shown by immunofluorescence analysis (Figure 5B).
Localization (localization) of Col11a1 in stellate cells
1) Confidence 0.65 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2876060 Disease Relevance 1.15 Pain Relevance 0.03
Secretion due to COLL, but not to TH, required extracellular Ca++ and was accompanied by increased uptake of 45Ca which was inhibited by local anesthetics.
Localization (Secretion) of COLL associated with local anesthetic
2) Confidence 0.53 Published 1976 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 772186 Disease Relevance 0 Pain Relevance 0.27
Henroitin et al. prepared rabbit antisera to a denaturation neoepitope, Coll 2-1, that corresponds to a peptide localized to another part of the helical domain of type II collagen (Deberg et al. 2002; Henrotin et al. 2004).
Localization (localized) of Coll 2-1
3) Confidence 0.04 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2716783 Disease Relevance 1.02 Pain Relevance 0.34

General Comments

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