INT350342

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.48
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tbp) DNA binding (Tbp) transcription factor binding (Tbp)
cytoplasm (Tbp)
Tbp (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 126 100.00 Very High Very High Very High
agonist 44 96.80 Very High Very High Very High
Action potential 10 70.88 Quite High
isoflurane 2 46.32 Quite Low
Hippocampus 20 42.04 Quite Low
Pyramidal cell 30 21.08 Low Low
potassium channel 12 17.84 Low Low
depression 6 12.88 Low Low
antagonist 14 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 14 91.80 High High
Schizophrenia 2 84.68 Quite High
Disease 6 83.96 Quite High
Depression 6 12.88 Low Low
Camurati-engelmann Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Spontaneous Rupture 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In agreement with our previous results, no LTP was induced by TBP (Figure 2B; 126% ± 10% control versus 136% ± 20% test pathway, n = 12, p > 0.05).
TBP Positive_regulation (induced) of LTP associated with long-term potentiation
1) Confidence 0.25 Published 2010 Journal Neuron Section Body Doc Link PMC3003154 Disease Relevance 0 Pain Relevance 0.29
Since TBP does not induce LTP in control conditions, the facilitation by M1 receptor activation is seen as a gating of LTP.
TBP Neg (not) Positive_regulation (induce) of LTP associated with long-term potentiation
2) Confidence 0.15 Published 2010 Journal Neuron Section Body Doc Link PMC3003154 Disease Relevance 0.48 Pain Relevance 0.36

General Comments

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