INT350343

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin1) plasma membrane (Grin1) nucleus (Csnk2a2)
enzyme binding (Grin1) cell cycle (Csnk2a2) kinase activity (Csnk2a2)
Anatomy Link Frequency
hippocampus 1
Csnk2a2 (Mus musculus)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 20 91.36 High High
noradrenaline 2 74.80 Quite High
long-term potentiation 126 50.28 Quite High
Calcium channel 2 17.20 Low Low
potassium channel 12 8.00 Low Low
agonist 44 5.00 Very Low Very Low Very Low
Pyramidal cell 30 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
Action potential 10 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 85.24 High High
Cognitive Disorder 14 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Camurati-engelmann Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Spontaneous Rupture 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CK2 also has direct effects on NMDAR function (Lieberman and Mody, 1999; Sanz-Clemente et al., 2010).
CK2 Regulation (effects) of NMDAR
1) Confidence 0.11 Published 2010 Journal Neuron Section Body Doc Link PMC3003154 Disease Relevance 0 Pain Relevance 0.04
There is emerging evidence demonstrating that CK2 directly modulates NMDAR (Lieberman and Mody, 1999) or regulates NMDAR subunit complement (Sanz-Clemente et al., 2010), and our results showing a SK channel-independent modulation of EPSP duration (Figure 7) potentially support such roles for CK2 at Schaffer collateral synapses in the hippocampus.
CK2 Regulation (regulates) of NMDAR in hippocampus associated with hippocampus
2) Confidence 0.07 Published 2010 Journal Neuron Section Body Doc Link PMC3003154 Disease Relevance 0.09 Pain Relevance 0.07

General Comments

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