INT350441

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ATF3) nucleolus (ATF3) nucleus (ATF3)
Anatomy Link Frequency
colon 2
ATF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 51 99.84 Very High Very High Very High
Cancer 79 95.92 Very High Very High Very High
Pressure And Volume Under Development 2 77.36 Quite High
Carcinoma 5 72.48 Quite High
Metastasis 14 54.80 Quite High
Shock 8 50.00 Quite Low
Malignant Neoplastic Disease 4 14.40 Low Low
Apoptosis 6 5.60 Low Low
Stress 5 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that ATF3 is likely to be down-regulated in colon cancers, hence supporting the rationale of therapeutically inducing ATF3 expression in this cancer entity.


Negative_regulation (regulated) of Negative_regulation (down) of ATF3 in colon associated with cancer and colon cancer
1) Confidence 0.43 Published 2010 Journal BMC Cancer Section Body Doc Link PMC3003660 Disease Relevance 1.62 Pain Relevance 0

General Comments

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