INT350483

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Myd88, Tlr2, Tirap) intracellular (Myd88, Tlr2, Tirap) cytoplasm (Myd88, Tlr2, Tirap)
plasma membrane (Myd88, Tlr2) cytosol (Myd88) protein complex (Myd88)
Myd88 (Mus musculus)
Tlr2 (Mus musculus)
Tirap (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 22 65.76 Quite High
Inflammation 8 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 2 53.52 Quite High
Myocardial Infarction 27 45.04 Quite Low
Injury 11 5.00 Very Low Very Low Very Low
Hypertrophy 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 9 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Reperfusion Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MyD88-dependent signalling via TLR2 and TLR4 requires the presence of TIRAP and will end after several steps in activation of NF?
MyD88-dependent Binding (signalling) of TLR2 Positive_regulation (requires) of TIRAP Binding (presence) of
1) Confidence 0.18 Published 2010 Journal Heart Fail Rev Section Body Doc Link PMC3003782 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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