INT35059

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Context Info
Confidence 0.88
First Reported 1987
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 4.61
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PLAUR) extracellular region (PLAUR) plasma membrane (PLAUR)
enzyme binding (PLAUR)
Anatomy Link Frequency
extracellular matrix 1
PLAUR (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 1 99.00 Very High Very High Very High
palliative 1 96.64 Very High Very High Very High
chemokine 1 94.36 High High
Inflammation 6 87.64 High High
cytokine 1 84.24 Quite High
abdominal pain 1 81.12 Quite High
Pain 1 79.64 Quite High
metalloproteinase 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis Related Under Development 3 99.42 Very High Very High Very High
Headache 1 99.00 Very High Very High Very High
Disease 1 98.88 Very High Very High Very High
Cancer 30 98.72 Very High Very High Very High
Thrombosis 6 97.68 Very High Very High Very High
Metastasis 3 97.28 Very High Very High Very High
Convulsion 1 97.28 Very High Very High Very High
Inflammatory Bowel Disease 3 97.04 Very High Very High Very High
Coma 1 96.52 Very High Very High Very High
Colorectal Cancer 3 96.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Extensive cerebral venous thrombosis resistant to heparin: local fibrinolysis with urokinase].
Protein_catabolism (fibrinolysis) of urokinase associated with thrombosis related under development
1) Confidence 0.88 Published 1997 Journal Rev. Neurol. (Paris) Section Title Doc Link 9296147 Disease Relevance 0.66 Pain Relevance 0.10
Fribrolysis with urokinase was performed.
Protein_catabolism (Fribrolysis) of urokinase
2) Confidence 0.61 Published 2004 Journal Ann Vasc Surg Section Abstract Doc Link 15164265 Disease Relevance 0.98 Pain Relevance 0.08
Urokinase has been implicated in tissue degradation as well as fibrinolysis and may play a role in tumour invasion and metastasis in human colorectal neoplasia.
Protein_catabolism (degradation) of Urokinase associated with colorectal cancer, cancer and metastasis
3) Confidence 0.54 Published 1987 Journal Br J Surg Section Abstract Doc Link 3111578 Disease Relevance 1.17 Pain Relevance 0.10
For example, uPA, uPAR and its inhibitor PAI-1 are responsible for the degradation and remodeling of the extracellular matrix, and are further involved in angiogenesis, cell adhesion and migration necessary for tumor cell invasion and metastasis [31,32].
Protein_catabolism (degradation) of uPAR in extracellular matrix associated with cancer, metastasis and adhesions
4) Confidence 0.51 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1779463 Disease Relevance 1.25 Pain Relevance 0.21
[Fibrinogen-guided thrombolysis with urokinase of a portal and mesenterial venous thrombosis during an acute episode of ulcerative colitis].
Protein_catabolism (thrombolysis) of urokinase associated with inflammatory bowel disease and thrombosis related under development
5) Confidence 0.01 Published 2006 Journal Dtsch. Med. Wochenschr. Section Title Doc Link 16418946 Disease Relevance 0.56 Pain Relevance 0.12

General Comments

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