INT350667

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Context Info
Confidence 0.29
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Stat5a) nucleus (Stat5a) DNA binding (Stat5a)
cytoplasm (Stat5a) signal transducer activity (Stat5a)
Stat5a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 54 98.88 Very High Very High Very High
addiction 2 60.28 Quite High
Multiple sclerosis 316 5.00 Very Low Very Low Very Low
Inflammation 56 5.00 Very Low Very Low Very Low
Central nervous system 54 5.00 Very Low Very Low Very Low
tolerance 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Demyelination 8 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 92 94.24 High High
Repression 18 82.60 Quite High
Demyelinating Disease 350 56.32 Quite High
Disease 136 5.00 Very Low Very Low Very Low
INFLAMMATION 70 5.00 Very Low Very Low Very Low
Central Nervous System Disease 54 5.00 Very Low Very Low Very Low
Multiple Sclerosis 40 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 20 5.00 Very Low Very Low Very Low
Cancer 16 5.00 Very Low Very Low Very Low
Death 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
miR-155 deficiency in Treg cells results in increased suppressor of cytokine signaling 1 (SOCS1) expression accompanied by impaired activation of signal transducer and activator of transcription 5 (STAT5) transcription factor in response to limiting amounts of IL-2.
Positive_regulation (activation) of Transcription (transcription) of STAT5 associated with cytokine
1) Confidence 0.29 Published 2011 Journal Autoimmune Diseases Section Body Doc Link PMC3003960 Disease Relevance 0.23 Pain Relevance 0.08
miR-155 deficiency in Treg cells results in increased suppressor of cytokine signaling 1 (SOCS1) expression accompanied by impaired activation of signal transducer and activator of transcription 5 (STAT5) transcription factor in response to limiting amounts of IL-2.
Positive_regulation (activation) of Transcription (transcription) of signal transducer and activator of transcription 5 associated with cytokine
2) Confidence 0.29 Published 2011 Journal Autoimmune Diseases Section Body Doc Link PMC3003960 Disease Relevance 0.23 Pain Relevance 0.08

General Comments

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