INT350862

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.35
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hist1h1t) chromosome (Hist1h1t) nucleus (Hist1h1t)
intracellular (Hist1h1t) DNA binding (Hist1h1t)
Hist1h1t (Rattus norvegicus)
Kcnj5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
potassium channel 51 100.00 Very High Very High Very High
ischemia 18 84.88 Quite High
Calcium channel 42 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reperfusion Injury 9 85.64 High High
Cv Unclassified Under Development 21 84.88 Quite High
Arrhythmia Under Development 33 83.96 Quite High
Myocardial Infarction 9 75.60 Quite High
Infarction 3 52.28 Quite High
Death 3 25.20 Quite Low
Heart Arrhythmia 6 17.96 Low Low
Coronary Heart Disease 3 5.00 Very Low Very Low Very Low
Headache 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first study10 about the action of H2S on ion channels was from Zhao’s study, and they studied the effects of H2S on KATP.
H2S Regulation (effects) of KATP associated with potassium channel
1) Confidence 0.02 Published 2010 Journal Journal of Cardiovascular Disease Research Section Body Doc Link PMC3004170 Disease Relevance 0.40 Pain Relevance 0.41
They proved the opening effect of H2S on KATP channel through three different levels.
H2S Regulation (effect) of KATP associated with potassium channel
2) Confidence 0.01 Published 2010 Journal Journal of Cardiovascular Disease Research Section Body Doc Link PMC3004170 Disease Relevance 0.50 Pain Relevance 0.44
Most of these studies showed that H2S exerts its function through acting on different ion channels.89

Effects of H2S on ATP dependent potassium channel (KATP)

H2S Regulation (acting) of KATP associated with potassium channel
3) Confidence 0.01 Published 2010 Journal Journal of Cardiovascular Disease Research Section Body Doc Link PMC3004170 Disease Relevance 0.44 Pain Relevance 0.36

General Comments

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