INT350901

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 1.59
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Pcsk4)
Anatomy Link Frequency
A431 1
Pcsk4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
topical agent 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
T-cell Lymphoma 1 99.50 Very High Very High Very High
Squamous Cell Carcinoma 2 99.44 Very High Very High Very High
Mycosis Fungoides 17 98.08 Very High Very High Very High
Malignant Neoplastic Disease 17 97.22 Very High Very High Very High
Sezary Syndrome 14 96.72 Very High Very High Very High
Lymphatic System Cancer 11 94.56 High High
Apoptosis 30 93.86 High High
Cancer 7 5.00 Very Low Very Low Very Low
Wrinkles 5 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Photodynamic Therapy with the Silicon Phthalocyanine Pc 4 Induces Apoptosis in Mycosis Fungoides and Sezary Syndrome

Our current focus on the effects of Photodynamic Therapy (PDT) using silicon phthalocyanine Pc 4 photosensitizer on malignant T lymphocytes arose due to preclinical observations that Jurkat cells, common surrogate for human T cell lymphoma, were more sensitive to Pc 4-PDT-induced killing than epidermoid carcinoma A431 cells.

Positive_regulation (induced) of Pc 4 in A431 associated with squamous cell carcinoma, t-cell lymphoma, malignant neoplastic disease, sezary syndrome, mycosis fungoides and apoptosis
1) Confidence 0.08 Published 2010 Journal Advances in Hematology Section Title Doc Link PMC3004392 Disease Relevance 1.59 Pain Relevance 0

General Comments

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