INT351007

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.33
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (IL2RA) extracellular space (IL2) extracellular region (IL2)
cell adhesion (IL2) plasma membrane (IL2RA) cell-cell signaling (IL2)
Anatomy Link Frequency
IL2R 2
IL2 (Homo sapiens)
IL2RA (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 2 95.36 Very High Very High Very High
tolerance 2 91.44 High High
Paracetamol 6 77.88 Quite High
cytokine 6 59.92 Quite High
rheumatoid arthritis 2 34.72 Quite Low
pruritus 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Antihistamine 4 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diphtheria 14 95.56 Very High Very High Very High
Cancer 12 78.52 Quite High
Htlv Types I And Ii 6 74.44 Quite High
Fever 4 74.24 Quite High
Lymphatic System Cancer 78 70.40 Quite High
Leukemia 8 69.88 Quite High
Death 6 61.60 Quite High
Apoptosis 4 61.16 Quite High
Autoimmune Disease 4 51.16 Quite High
Graft Vs Host Disease 4 49.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Denileukin diftitox binds to IL2R in the same way as IL2 because it contains the full-length sequence of IL2.
IL2 Binding (binds) of IL2R in IL2R
1) Confidence 0.33 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.45 Pain Relevance 0.17
Unlike daclizumab (anti-Tac), which is a mAb directed against the CD25 component of the receptor, DAB486-IL2 contained the full-length sequence of IL2 as the ligand for the IL2R.
DAB486-IL2 Binding (ligand) of IL2R in IL2R
2) Confidence 0.29 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.88 Pain Relevance 0.09

General Comments

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