INT351010

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ISG20) intracellular (ISG20) cell-cell signaling (IL2)
cell proliferation (ISG20) extracellular space (IL2) extracellular region (IL2)
Anatomy Link Frequency
IL2R 2
ISG20 (Homo sapiens)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 99.56 Very High Very High Very High
pruritus 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 3 74.76 Quite High
Diphtheria 7 67.36 Quite High
Lymphatic System Cancer 39 66.96 Quite High
Leukemia 4 64.80 Quite High
Htlv Types I And Ii 3 61.52 Quite High
Disease 20 59.04 Quite High
Immunodeficiency 1 26.16 Quite Low
Malignant Neoplastic Disease 5 22.32 Low Low
Syndrome 12 5.56 Low Low
Mycosis Fungoides 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We know now that the IL2R is a complex comprised by three parts: the alpha chain (CD25) which is required for high affinity binding, the beta chain (CD122) which participates in IL2 and IL15 signal transduction, and the common gamma chain (CD132) which participates in downstream signal transduction of IL2 and other cytokines.11–14
CD25 Positive_regulation (participates) of Transcription (transduction) of IL2 in IL2R associated with cytokine
1) Confidence 0.31 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.46 Pain Relevance 0.05

General Comments

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