INT351011

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HDAC9, TSPYL2) cytoplasm (HDAC9, TSPYL2) nucleoplasm (TSPYL2)
nucleolus (TSPYL2) plasma membrane (TSPYL2) transcription factor binding (HDAC9)
HDAC9 (Homo sapiens)
TSPYL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 83.92 Quite High
depression 1 21.20 Low Low
pruritus 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 39 100.00 Very High Very High Very High
Disease 20 68.40 Quite High
Syndrome 12 64.64 Quite High
Mycosis Fungoides 12 64.52 Quite High
Cancer 6 61.92 Quite High
Leukemia 4 55.00 Quite High
Pain 1 35.84 Quite Low
Anxiety Disorder 1 22.16 Low Low
Depression 1 21.20 Low Low
Diphtheria 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since HDAC inhibitors are clinically active compounds in CTCL, combination therapies to test potential synergism with denileukin diftitox are warranted.


HDAC Binding (compounds) of CTCL associated with lymphatic system cancer
1) Confidence 0.04 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.63 Pain Relevance 0.08

General Comments

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