INT351019

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EEF2) translation (EEF2) GTPase activity (EEF2)
cytoplasm (EEF2)
EEF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 59.16 Quite High
pruritus 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 3 98.76 Very High Very High Very High
Diphtheria 7 98.42 Very High Very High Very High
Immunodeficiency 1 55.64 Quite High
Malignant Neoplastic Disease 5 51.80 Quite High
Disease 20 50.80 Quite High
Syndrome 12 35.04 Quite Low
Exfoliative Dermatitis 2 26.36 Quite Low
Cancer 6 25.72 Quite Low
Mycosis Fungoides 12 19.76 Low Low
Metastasis 1 17.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The fragment of diphtheria toxin is translocated across the endosomal membrane into the cytosol where it inhibits protein synthesis via ADP-ribosylation of elongation factor-2, ultimately resulting in cell death.9,10
Negative_regulation (inhibits) of elongation factor-2 Binding (ribosylation) of associated with diphtheria and death
1) Confidence 0.03 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.53 Pain Relevance 0.03

General Comments

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