INT351085

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGFR, TXK) nucleus (EGFR, TXK) cytoplasm (EGFR, TXK)
DNA binding (TXK) extracellular space (EGFR) endosome (EGFR)
EGFR (Homo sapiens)
TXK (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 21 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
carbamazepine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Advanced Or Metastatic Breast Cancer 28 91.20 High High
Cancer 35 64.80 Quite High
Breast Cancer 16 59.76 Quite High
Disease 45 22.68 Low Low
Toxicity 12 15.84 Low Low
Death 5 14.80 Low Low
Diarrhoea 25 5.00 Very Low Very Low Very Low
Exanthema 19 5.00 Very Low Very Low Very Low
Metastasis 16 5.00 Very Low Very Low Very Low
Vomiting 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ligand binding of these ErbB receptors causes formation of heterodimers or homodimers, in turn inducing autophosphorylation of specific tyrosine kinase residues within conserved catalytic domains of the ErbB receptors.
ErbB Binding (binding) of Positive_regulation (inducing) of Phosphorylation (autophosphorylation) of tyrosine kinase
1) Confidence 0.04 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004582 Disease Relevance 0.35 Pain Relevance 0

General Comments

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