INT351277

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 5.79
Pain Relevance 2.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FMOD) extracellular region (FMOD) proteinaceous extracellular matrix (FMOD)
intracellular (FMOD)
FMOD (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 441 100.00 Very High Very High Very High
Central nervous system 15 100.00 Very High Very High Very High
Neuropathic pain 6 100.00 Very High Very High Very High
depression 54 79.12 Quite High
cytokine 3 77.80 Quite High
Peripheral sensitization 3 74.52 Quite High
Neurotransmitter 15 70.92 Quite High
behavioral therapy 3 60.56 Quite High
central sensitization 3 60.36 Quite High
Acupuncture 3 58.96 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 441 100.00 Very High Very High Very High
Depression 102 100.00 Very High Very High Very High
Neuropathic Pain 9 100.00 Very High Very High Very High
Disease 3 96.60 Very High Very High Very High
Chronic Disease 3 91.16 High High
Fatigue 48 82.88 Quite High
Cognitive Disorder 30 81.28 Quite High
Anxiety Disorder 45 80.24 Quite High
Congenital Anomalies 21 76.04 Quite High
Pain 243 55.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent research suggests that these conditions are in fact differential symptom presentations of a single underlying condition, and that major depressive disorder (MDD) and FM (as well as neuropathic pain) are both associated with neuroplastic changes in the CNS.13 However, in a recent review of the relationship between FM and MDD, Pae et al assert that currently available findings do not support the assumption that MDD and FM refer to the same underlying construct, nor can they be seen as subsidiaries of one disease concept.14
Positive_regulation (between) of Gene_expression (assumption) of FM associated with depression, neuropathic pain, central nervous system, disease and fibrositis
1) Confidence 0.10 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.86 Pain Relevance 0.73
Recent research suggests that these conditions are in fact differential symptom presentations of a single underlying condition, and that major depressive disorder (MDD) and FM (as well as neuropathic pain) are both associated with neuroplastic changes in the CNS.13 However, in a recent review of the relationship between FM and MDD, Pae et al assert that currently available findings do not support the assumption that MDD and FM refer to the same underlying construct, nor can they be seen as subsidiaries of one disease concept.14
Neg (not) Positive_regulation (support) of Gene_expression (assumption) of FM associated with depression, neuropathic pain, central nervous system, disease and fibrositis
2) Confidence 0.10 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.83 Pain Relevance 0.66
Recent research suggests that these conditions are in fact differential symptom presentations of a single underlying condition, and that major depressive disorder (MDD) and FM (as well as neuropathic pain) are both associated with neuroplastic changes in the CNS.13 However, in a recent review of the relationship between FM and MDD, Pae et al assert that currently available findings do not support the assumption that MDD and FM refer to the same underlying construct, nor can they be seen as subsidiaries of one disease concept.14
Positive_regulation (between) of Gene_expression (disorder) of FM associated with depression, neuropathic pain, central nervous system, disease and fibrositis
3) Confidence 0.10 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 2.10 Pain Relevance 0.87

General Comments

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