INT351278

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 1
Speculated 3
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 6.45
Pain Relevance 5.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FMOD) extracellular region (FMOD) proteinaceous extracellular matrix (FMOD)
intracellular (FMOD)
Anatomy Link Frequency
nervous system 1
FMOD (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 735 100.00 Very High Very High Very High
pregabalin 315 100.00 Very High Very High Very High
Pain 285 99.96 Very High Very High Very High
depression 90 98.60 Very High Very High Very High
Pain score 80 96.32 Very High Very High Very High
Duloxetine 420 94.68 High High
Analgesic 10 86.16 High High
tricyclic antidepressant 35 83.12 Quite High
sSRI 35 80.40 Quite High
Acupuncture 5 78.96 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 735 100.00 Very High Very High Very High
Pain 405 99.96 Very High Very High Very High
Depression 170 98.60 Very High Very High Very High
Anxiety Disorder 75 98.04 Very High Very High Very High
Temporomandibular Joint Disorders 15 97.84 Very High Very High Very High
Nervous System Malformation 10 94.80 High High
Fatigue 80 91.28 High High
Cognitive Disorder 50 77.68 Quite High
INFLAMMATION 10 71.04 Quite High
Disease 5 61.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding may have considerable implications for FM treatment if replicated by larger studies, as FM and TMD often occur comorbidly.71
Spec (implications) Regulation (implications) of FM associated with temporomandibular joint disorders and fibrositis
1) Confidence 0.09 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.63 Pain Relevance 0.93
However, these new therapeutic agents are still not effective for all FM patients.
Neg (not) Regulation (effective) of FM associated with fibrositis
2) Confidence 0.09 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.10 Pain Relevance 0.91
The number of randomized controlled trials for FM treatment modalities has risen steadily over the past decade,4 with pharmaceutical studies focusing on compounds that target the nervous system abnormalities implicated in the condition.
Regulation (trials) of FM in nervous system associated with nervous system malformation and fibrositis
3) Confidence 0.09 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.44 Pain Relevance 1.05
The 13-week trial58 examined the effect of pregabalin on FM pain and symptom management.
Spec (examined) Regulation (effect) of FM associated with pain, pregabalin and fibrositis
4) Confidence 0.09 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.19 Pain Relevance 1.53
The smaller study, published in 2009, randomized 888 FM patients to similar groups to examine the effect of milnacipran on FM and the pain of FM over a 6-month period.
Spec (examine) Regulation (effect) of FM associated with pain and fibrositis
5) Confidence 0.06 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 1.09 Pain Relevance 0.74

General Comments

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