INT351303

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cnr2) plasma membrane (Cnr2) signal transducer activity (Cnr2)
Anatomy Link Frequency
brain 2
Cnr2 (Mus musculus)
Pain Link Frequency Relevance Heat
analgesia 10 98.92 Very High Very High Very High
Neuropathic pain 38 95.04 Very High Very High Very High
Cannabinoid 7 93.68 High High
Analgesic 22 92.92 High High
Cannabinoid receptor 5 90.96 High High
Spinal cord 8 90.72 High High
Pain 67 89.52 High High
Peripheral nervous system 2 87.64 High High
hyperexcitability 3 78.44 Quite High
adjuvant analgesic 2 71.12 Quite High
Disease Link Frequency Relevance Heat
Sleep Disorders 1 98.48 Very High Very High Very High
Dizziness 1 97.92 Very High Very High Very High
Neuropathic Pain 46 95.04 Very High Very High Very High
Pain 79 89.52 High High
Neuralgia 1 27.36 Quite Low
Herpes Simplex Virus Infection 1 26.96 Quite Low
Cancer 2 25.12 Quite Low
Low Back Pain 52 5.00 Very Low Very Low Very Low
Osteoarthritis 38 5.00 Very Low Very Low Very Low
INFLAMMATION 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have shown selective targeting of peripheral and spinal CB1 and CB2 receptors are promising targets for analgesia because they may avoid the psychoactivity of brain CB1 receptor activation and may allow the administration of doses that produce a greater analgesic effect with reduced psychoactivity.60

Cannabinoid receptor pharmacology

Regulation (targeting) of CB2 Binding (receptors) of in brain associated with cannabinoid receptor, analgesic and analgesia
1) Confidence 0.10 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004649 Disease Relevance 0.66 Pain Relevance 1.39

General Comments

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