INT351354

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 6.93
Pain Relevance 5.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lpar1) cytoplasm (Lpar1) signal transducer activity (Lpar1)
Anatomy Link Frequency
neurons 3
Lpar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 265 99.84 Very High Very High Very High
qutenza 120 99.76 Very High Very High Very High
Cancer pain 100 93.72 High High
Pain 45 88.08 High High
Kinase C 185 87.20 High High
nociceptor 30 84.88 Quite High
antagonist 30 82.80 Quite High
Lasting pain 10 80.44 Quite High
Thermal hyperalgesia 25 77.00 Quite High
allodynia 25 76.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 270 99.84 Very High Very High Very High
Bone Cancer 215 99.80 Very High Very High Very High
Cancer 165 92.08 High High
Carcinoma 15 90.84 High High
Pain 55 88.08 High High
Targeted Disruption 5 87.00 High High
Nociception 25 82.12 Quite High
Hyperalgesia 25 77.00 Quite High
Neuropathic Pain 80 76.00 Quite High
Injury 10 75.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-localization of TRPV1 and EDG-2 in a same neuron provides the basis for their cross-talk.


Localization (localization) of EDG-2 in neuron
1) Confidence 0.40 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 0.80 Pain Relevance 0.45
Co-localization of TRPV1 and LPA1 receptor in DRG neurons
Localization (localization) of LPA1 receptor in neurons associated with dorsal root ganglion
2) Confidence 0.40 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 0.93 Pain Relevance 0.65
The findings that co-localization of TRPV1 and LPA1 receptor EDG-2 and bone cancer induced an increase in LPA1 receptor expression in DRG [40] provide further support for these phenomena.
Localization (localization) of LPA1 receptor associated with dorsal root ganglion and bone cancer
3) Confidence 0.38 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 1.90 Pain Relevance 1.39
The findings that co-localization of TRPV1 and LPA1 receptor EDG-2 and bone cancer induced an increase in LPA1 receptor expression in DRG [40] provide further support for these phenomena.
Localization (localization) of EDG-2 associated with dorsal root ganglion and bone cancer
4) Confidence 0.38 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 1.96 Pain Relevance 1.42
Immunohistochemistry staining revealed a high co-localization of LPA1 with TRPV1 in DRG neurons.
Localization (localization) of LPA1 in neurons associated with dorsal root ganglion
5) Confidence 0.35 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC3004845 Disease Relevance 1.33 Pain Relevance 1.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox