INT351355

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.94
Pain Relevance 2.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lpar1) cytoplasm (Lpar1) signal transducer activity (Lpar1)
Lpar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 106 98.72 Very High Very High Very High
Cancer pain 40 91.40 High High
Kinase C 74 90.08 High High
Pain 18 88.08 High High
nociceptor 12 87.76 High High
Inflammatory mediators 4 77.28 Quite High
Thermal hyperalgesia 10 77.00 Quite High
allodynia 10 76.00 Quite High
antagonist 12 72.44 Quite High
Neuropathic pain 20 70.32 Quite High
Disease Link Frequency Relevance Heat
Bone Cancer 86 100.00 Very High Very High Very High
Ganglion Cysts 108 98.72 Very High Very High Very High
Pain 22 88.08 High High
Targeted Disruption 2 87.00 High High
Nociception 10 82.12 Quite High
INFLAMMATION 14 77.28 Quite High
Hyperalgesia 10 77.00 Quite High
Neuropathic Pain 32 76.00 Quite High
Stress 2 24.20 Low Low
Nervous System Injury 2 23.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The findings that co-localization of TRPV1 and LPA1 receptor EDG-2 and bone cancer induced an increase in LPA1 receptor expression in DRG [40] provide further support for these phenomena.
Positive_regulation (increase) of Localization (localization) of EDG-2 associated with dorsal root ganglion and bone cancer
1) Confidence 0.25 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 1.97 Pain Relevance 1.43
The findings that co-localization of TRPV1 and LPA1 receptor EDG-2 and bone cancer induced an increase in LPA1 receptor expression in DRG [40] provide further support for these phenomena.
Positive_regulation (increase) of Localization (localization) of LPA1 receptor associated with dorsal root ganglion and bone cancer
2) Confidence 0.25 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 1.97 Pain Relevance 1.43

General Comments

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