INT351365

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.79
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LPA, Il6) extracellular space (Il6) peptidase activity (LPA)
transport (LPA) aging (Il6) small molecule metabolic process (LPA)
Anatomy Link Frequency
blood platelets 2
LPA (Homo sapiens)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 100.00 Very High Very High Very High
Neuropathic pain 10 87.52 High High
Demyelination 2 85.20 High High
Cancer pain 20 80.32 Quite High
Inflammation 5 76.52 Quite High
Pain 9 67.64 Quite High
dorsal root ganglion 53 61.96 Quite High
Kinase C 37 24.88 Low Low
qutenza 24 5.00 Very Low Very Low Very Low
withdrawal 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 33 100.00 Very High Very High Very High
Metastasis 1 100.00 Very High Very High Very High
Ovarian Cancer 1 99.00 Very High Very High Very High
Neuropathic Pain 16 87.52 High High
Adhesions 1 86.72 High High
Demyelinating Disease 2 85.20 High High
Injury 2 83.68 Quite High
Bone Cancer 43 80.12 Quite High
Cancer Pain 3 79.32 Quite High
INFLAMMATION 7 76.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Released by activated blood platelets [8], LPA promotes progression of bone metastases by inducing secretion of tumor-derived cytokine (IL-6 and IL-8) in breast and ovarian cancer cells [9,10].
LPA Positive_regulation (inducing) of Localization (secretion) of IL-6 in blood platelets associated with cancer, ovarian cancer, metastasis and cytokine
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 1.79 Pain Relevance 0.54

General Comments

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