INT351366

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 1.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LPA) small molecule metabolic process (LPA) Golgi apparatus (Rab38)
endoplasmic reticulum (Rab38) GTPase activity (Rab38) cytoplasm (Rab38)
Anatomy Link Frequency
nociceptor 1
LPA (Homo sapiens)
Rab38 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 100.00 Very High Very High Very High
Neuropathic pain 10 99.32 Very High Very High Very High
substance P 3 98.68 Very High Very High Very High
Cancer pain 20 98.48 Very High Very High Very High
nociceptor 6 97.68 Very High Very High Very High
dorsal root ganglion 53 96.36 Very High Very High Very High
Kinase C 37 91.60 High High
sodium channel 1 87.20 High High
nav1.8 2 86.00 High High
Pain 9 78.96 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 16 99.32 Very High Very High Very High
Bone Cancer 43 98.28 Very High Very High Very High
Nociception 5 96.84 Very High Very High Very High
Ganglion Cysts 54 96.36 Very High Very High Very High
Pain 11 78.96 Quite High
INFLAMMATION 7 74.20 Quite High
Targeted Disruption 1 14.92 Low Low
Cancer 33 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Carcinoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, LPA can increase tetrodotoxin-resistant (TTX-R) sodium current [59] and induce substance P release from nociceptor endings [60].
LPA Positive_regulation (increase) of TTX-R in nociceptor associated with tetrodotoxin, nociceptor and substance p
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 0.95 Pain Relevance 1.53

General Comments

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