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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid metabolic process (LPA, Trpv1) cytosol (Trpv1) peptidase activity (LPA)
transport (LPA) small molecule metabolic process (LPA) extracellular region (LPA)
Anatomy Link Frequency
neurons 1
LPA (Homo sapiens)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 10 90.56 High High
Pain 9 89.92 High High
substance P 3 83.64 Quite High
Kinase C 37 82.40 Quite High
antagonist 6 79.44 Quite High
Cancer pain 20 74.56 Quite High
intrathecal 7 68.96 Quite High
Inflammation 5 62.00 Quite High
dorsal root ganglion 53 60.16 Quite High
withdrawal 9 55.68 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 16 90.56 High High
Pain 11 89.92 High High
Bone Cancer 43 88.48 High High
Clostridium Infection 2 87.12 High High
Cancer 33 63.04 Quite High
INFLAMMATION 7 62.00 Quite High
Ganglion Cysts 54 60.16 Quite High
Nociception 5 45.36 Quite Low
Hyperalgesia 5 22.16 Low Low
Carcinoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
l) was delivered intracellularly, LPA still increased TRPV1 currents in 14 out of 23 neurons (Figure 5D, F, p < 0.001), suggesting that Rho may not be an important signal molecule in modulation of TRPV1 by LPA.
LPA Regulation (modulation) of TRPV1 in neurons
1) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004845 Disease Relevance 0.83 Pain Relevance 0.69

General Comments

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