INT351373

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) signal transduction (Ngf) extracellular space (Ngf)
extracellular region (Ngf) plasma membrane (Ntrk1) kinase activity (Ntrk1)
Anatomy Link Frequency
skeleton 2
Ngf (Mus musculus)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 25 100.00 Very High Very High Very High
c fibre 4 99.16 Very High Very High Very High
nociceptor 4 93.28 High High
Neurotransmitter 1 86.28 High High
unmyelinated 2 72.32 Quite High
Pain 30 68.72 Quite High
Analgesic 5 60.40 Quite High
Cancer pain 23 58.00 Quite High
Inflammation 6 34.24 Quite Low
Spinal cord 1 21.84 Low Low
Disease Link Frequency Relevance Heat
Cancer 55 100.00 Very High Very High Very High
Bone Fracture 1 69.84 Quite High
Pain 31 68.72 Quite High
Bone Cancer 13 57.80 Quite High
Neuroma 25 50.00 Quite Low
Sarcoma 8 50.00 Quite Low
Femoral Fractures 1 43.44 Quite Low
INFLAMMATION 6 34.24 Quite Low
Injury 5 33.16 Quite Low
Hyperalgesia 3 25.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The NGF produced by target tissues or tumor cells activates TrkA receptors expressed on the terminals of C-fibers [18,22] presumably including those innervating the skeleton.
NGF Positive_regulation (activates) of Gene_expression (expressed) of TrkA in skeleton associated with c fibre, nerve growth factor and cancer
1) Confidence 0.35 Published 2010 Journal Mol Pain Section Body Doc Link PMC3004846 Disease Relevance 0.41 Pain Relevance 1.18

General Comments

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