INT351512

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NMD3) nucleolus (NMD3) nucleus (NMD3)
cytoplasm (NMD3)
NMD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 50.36 Quite High
imagery 2 23.28 Low Low
Potency 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Dysautonomia 196 99.20 Very High Very High Very High
Disease 13 57.88 Quite High
Pneumonia 1 52.00 Quite High
Pain 2 50.36 Quite High
Vomiting 1 48.88 Quite Low
Cardiovascular Disease 1 48.48 Quite Low
Adhesions 2 40.00 Quite Low
Congenital Anomalies 2 39.40 Quite Low
Neuropathic Pain 3 29.56 Quite Low
Cognitive Disorder 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our system, treatment with cycloheximide, an inhibitor of NMD, did not alter the level of the mutant transcript (data not shown); however, this is not consistent with observations from another study [12].
Negative_regulation (inhibitor) of NMD
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012102 Disease Relevance 0.31 Pain Relevance 0.05
Thus, we tested cycloheximide, a protein synthesis inhibitor which also inhibits NMD.
Negative_regulation (inhibits) of NMD
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004942 Disease Relevance 0.62 Pain Relevance 0

General Comments

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