INT351645

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Context Info
Confidence 0.24
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.96
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Enpep) peptidase activity (Enpep) plasma membrane (Enpep)
Anatomy Link Frequency
kidney 2
Enpep (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 6 88.32 High High
Kinase C 3 77.44 Quite High
antagonist 15 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-eclampsia 138 99.66 Very High Very High Very High
Increased Venous Pressure Under Development 9 96.48 Very High Very High Very High
Pre-term Labor 81 94.96 High High
Dysmenorrhea 6 88.32 High High
Hypertension 81 81.56 Quite High
Disease 6 61.36 Quite High
Premature Birth 18 13.76 Low Low
Benign Prostatic Hypertrophy 12 5.00 Very Low Very Low Very Low
Sprains And Strains 12 5.00 Very Low Very Low Very Low
Proteinuria 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the trophoblastic degeneration seen during severe preeclampsia may be due to a failure to synthesize APA and P-LAP.
Negative_regulation (failure) of Gene_expression (synthesize) of APA associated with pre-eclampsia
1) Confidence 0.24 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.84 Pain Relevance 0.09
They also showed that treatment with an ACE inhibitor reduced kidney APA activity in SHRs, suggesting that APA expression may be positively coupled with AngII levels.
Negative_regulation (coupled) of Gene_expression (expression) of APA in kidney
2) Confidence 0.20 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0 Pain Relevance 0.04
Much higher doses of APA revealed a sharp decline of BP (approximately 50?
Negative_regulation (revealed) of Gene_expression (doses) of APA
3) Confidence 0.18 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.12 Pain Relevance 0

General Comments

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