INT351656

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Context Info
Confidence 0.20
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Enpep) extracellular space (Agt) peptidase activity (Enpep)
plasma membrane (Enpep) extracellular matrix organization (Agt)
Enpep (Mus musculus)
Agt (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 4 33.72 Quite Low
antagonist 10 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-eclampsia 92 93.08 High High
Pre-term Labor 54 87.84 High High
Hypertension 54 81.88 Quite High
Adverse Drug Reaction 4 78.56 Quite High
Increased Venous Pressure Under Development 6 73.20 Quite High
Hypoxia 4 63.60 Quite High
Targeted Disruption 4 53.20 Quite High
Dysmenorrhea 4 33.72 Quite Low
Premature Birth 12 18.08 Low Low
Benign Prostatic Hypertrophy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
APA KO mice are hypersensitive to exogenously administered AngII, strongly suggesting the involvement of APA in this AngII sensitivity [50].
APA Regulation (involvement) of AngII
1) Confidence 0.20 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.62 Pain Relevance 0
Our basic and clinical research has shown that the placental and maternal barriers to the hormonal effects of these fetal peptides are the aminopeptidases: placental leucine aminopeptidase (P-LAP) (EC3.4.11.3) that acts on oxytocin (OT), vasopressin (AVP) [5–7], and aminopeptidase A (APA ) (EC3.4.11.7) that act on AngII, respectively, [8, 9] as presented in Figure 1.
APA Regulation (act) of AngII
2) Confidence 0.12 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.58 Pain Relevance 0

General Comments

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