INT351731

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) plasma membrane (ROS1)
SSD (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 41 99.84 Very High Very High Very High
Death 25 76.52 Quite High
Cervical Cancer 5 72.72 Quite High
Apoptosis 27 63.76 Quite High
Solid Tumor 2 30.08 Quite Low
Toxicity 1 25.64 Quite Low
Lung Cancer 4 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 3 5.00 Very Low Very Low Very Low
Ovarian Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our finding in this study also showed that both SSa and SSd induced significant cellular ROS accumulation in cancer cells, which substantially contribute to synergistic cytotoxicity in saikosaponin and cisplatin cotreated cell.
SSd Positive_regulation (induced) of Positive_regulation (accumulation) of ROS associated with cancer
1) Confidence 0.18 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3006358 Disease Relevance 0.71 Pain Relevance 0

General Comments

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