INT35184

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Context Info
Confidence 0.45
First Reported 1987
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.04
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (SNRPN) nucleus (SNRPN)
Anatomy Link Frequency
myometrium 1
chest 1
motor neurons 1
SNRPN (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 98.32 Very High Very High Very High
fibrosis 4 59.56 Quite High
cytokine 13 5.00 Very Low Very Low Very Low
chemokine 10 5.00 Very Low Very Low Very Low
Mechanotransduction 8 5.00 Very Low Very Low Very Low
Dismenorea 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 92 100.00 Very High Very High Very High
Myocardial Infarction 2 99.98 Very High Very High Very High
Cold Sores 203 99.40 Very High Very High Very High
Toxicity 5 99.28 Very High Very High Very High
Angina 1 98.32 Very High Very High Very High
Adhesions 94 97.20 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 44 96.96 Very High Very High Very High
Immunodeficiency 14 90.20 High High
Spinal Muscular Atrophy 1 75.48 Quite High
Disease 32 60.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Forty-two patients with acute myocardial infarction received 150-mg recombinant human tissue-type plasminogen activator (rt-PA) at 2.3 +/- 1.2 hours after the onset of chest pain.
Positive_regulation (received) of rt-PA in chest associated with angina and myocardial infarction
1) Confidence 0.45 Published 1987 Journal Am. J. Cardiol. Section Abstract Doc Link 3120567 Disease Relevance 0.33 Pain Relevance 0.10
Researchers at the University of Georgia hope to produce systems of motor neurons from hES cells to test the effectiveness and toxicity of drugs that offer the promise of increasing SMN protein levels [18].
Positive_regulation (increasing) of SMN protein in motor neurons associated with toxicity
2) Confidence 0.04 Published 2008 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2569955 Disease Relevance 0.64 Pain Relevance 0.03
Increases in SmAV protein levels in rat myometrium were demonstrated for pregnant day 16, day 20 and in labor samples.


Positive_regulation (Increases) of SmAV protein in myometrium
3) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759504 Disease Relevance 0 Pain Relevance 0
A newly produced SmAV-specific antibody demonstrates gestation-specific increases in SmAV protein levels and stretch-specific increases in SmAV association with focal adhesion proteins.
Positive_regulation (increases) of SmAV protein associated with adhesions
4) Confidence 0.01 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2759504 Disease Relevance 0.52 Pain Relevance 0
Using this HSV-2/SHIV-RT model in which the SHIV-RT infection frequency is enhanced, we tested whether a promising new generation microbicide (using Carraguard as the delivery vehicle) was still able to protect against SHIV-RT infection as it did in naïve animals [28].
Positive_regulation (enhanced) of SHIV-RT associated with cold sores and infection
5) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2787245 Disease Relevance 1.54 Pain Relevance 0

General Comments

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